Here is The Courier-Journal’s preseason girls basketball Top 25 poll, as voted on by the state’s coaches. Every coach in the state was given a ballot. A total of 70 replied. First-place votes in parentheses.
| Team | Region | 2015-16 record |
| 1. Butler (62) | Sixth | 31-5 |
| 2. Mercer County (3) | 12th | 31-6 |
| 3. Murray (2) | First | 35-2 |
| 4. Sacred Heart | Seventh | 23-8 |
| 5. Male (1) | Seventh | 29-3 |
| 6. Franklin County | 11th | 31-5 |
| 7. Bullitt East | Sixth | 21-6 |
| 8. Simon Kenton (1) | Eighth | 24-6 |
| 9. Elizabethtown | Fifth | 30-5 |
| 10. Holmes | Ninth | 29-5 |
| 11. Manual (1) | Seventh | 21-8 |
| 12. Mason County | 10th | 27-4 |
| 13. Mercy | Sixth | 22-12 |
| 14. Bowling Green | Fourth | 29-5 |
| 15. East Carter | 16th | 26-8 |
| 16. South Warren | Fourth | 23-8 |
| 17. Eastern | Seventh | 21-7 |
| 18. Ashland Blazer | 16th | 14-16 |
| 19. Breckinridge County | Third | 20-11 |
| 20. Henderson County | Second | 18-10 |
| 21. Campbell County | 10th | 25-10 |
| 22. Scott County | 11th | 18-8 |
| 23. Lafayette | 11th | 25-8 |
| 24. Clark County | 10th | 18-11 |
| 25. Lincoln County | 12th | 27-7 |